Health Effects of Vaping Smoking and Tobacco Use CDC Nonnicotine vapes may be marketed as safe, but many still contain chemicals, have unknown health effects, and aren't FDAregulated. Teens are using them more ofteneven alongside nicotine vapes. No ecigarette is risk free. Health effects of electronic cigarettes Wikipedia Toxicity, Chemistry, and Public Health Relevance of Emerging Nicotine Analog Vapes, Pods, and Pouches Chemical Research in Toxicology